Doxazosin Drug Interactions

Doxazosin drug interactions with other medications, such as cimetidine or vardenafil, can lead to problems. These interactions can increase the level of doxazosin in your blood or may increase your risk of developing dangerously low blood pressure. If doxazosin drug interactions are a concern, your healthcare provider may adjust your dosage or monitor you more closely.

An Overview of Doxazosin Drug Interactions

Doxazosin mesylate (Cardura®) can potentially interact with many drugs. Some of these Doxazosin drug interactions include:
 

Doxazosin Interactions Explained

The following sections explain in detail the various interactions that can occur when doxazosin is combined with any of the drugs listed above.
 
 
Cimetidine
Taking doxazosin with cimetidine can increase the level of doxazosin in your blood, perhaps increasing your risk of side effects. Your healthcare provider may need to adjust your dose of these medications or consider changing medications to avoid this interaction.
 
Sildenafil
Taking doxazosin and sildenafil together may increase your risk of dangerously low blood pressure (hypotension). As a result, your healthcare provider may need to adjust your dose of these medications. Be sure to talk with your healthcare provider before taking these two medications together.
 
Tadalafil
If doxazosin and tadalafil are combined, this may increase your risk of dangerously low blood pressure (hypotension). Your healthcare provider may adjust your dose of these medications to prevent this. Ask your healthcare provider about taking these two medications together in your particular situation.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD
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