A blood pressure reading consists of two numbers -- for example: 120/80. The top number is known as the systolic blood pressure, and the bottom number is the diastolic blood pressure. During clinical studies in people taking Cozaar, systolic blood pressure decreased, on average, by 5.5 to 10.5 mmHg. Diastolic blood pressure decreased by 3.5 to 7.5 mmHg, on average. Certain factors, such as dosage, affected how much the blood pressure dropped.
By lowering blood pressure, Cozaar can decrease the risks that are seen with long-term high blood pressure (see Effects of High Blood Pressure). This includes a stroke or heart attack.
For people with diabetic nephropathy, the effects of Cozaar have been shown to slow down the progression of diabetic nephropathy, resulting in less kidney damage and a decreased chance for developing serious complications (such as the need for kidney dialysis).
Some general considerations for when and how to take Cozaar include:
- The medication comes in tablet form. It is usually taken once or twice a day.
- Cozaar may be taken with or without food.
- Do not break, chew, or crush the tablets unless your healthcare provider instructs you to do so.
- The medication should be taken at the same time each day to maintain an even level in your blood.
- For Cozaar to work properly, you have to take it as prescribed. The medication will not work if you stop taking it.
The dose of Cozaar your healthcare provider recommends will vary, depending on a number of factors, including:
- The medical condition being treated
- Other medical conditions you may have
- Other medications you may be currently taking
- How you respond to the drug.
As with any medication, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
(Click Cozaar Dosage for more information.)