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Cozaar Interactions
When certain medicines are taken with Cozaar, drug interactions may occur and sometimes result in side effects or complications. For example, your body may metabolize the drugs differently than intended and significantly increase or decrease the drug levels in your system. Medicines that can potentially cause Cozaar interactions include: potassium-sparing diuretics, nonsteroidal anti-inflammatory drugs, rifampin, and potassium supplements or salt substitutes with potassium.
Cozaar Drug Interactions: An Overview
Cozaar® (losartan potassium) can potentially interact with a number of other medicines. Some of these Cozaar interactions can include:
- Angiotensin-converting enzyme inhibitors (ACE inhibitors), including:
- Benazepril (Lotensin®), benazepril-hydrochlorothiazide (Lotensin HCT®), or benazepril-amlodipine (Lotrel®)
- Captopril (Capoten®) or captopril-hydrochlorothiazide (Capozide®)
- Enalapril (Vasotec®), enalapril-hydrochlorothiazide (Vaseretic®), or enalapril-felodipine (Lexxel®)
- Fosinopril (Monopril®) or fosinopril-hydrochlorothiazide (Monopril-HCT®)
- Lisinopril (Prinivil®, Zestril®) or lisinopril-hydrochlorothiazide (Prinzide®, Zestoretic®)
- Quinapril (Accupril®) or quinapril-hydrochlorothiazide (Accuretic®, Quinaretic)
- Ramipril (Altace®)
- Diuretics, such as torsemide (Demadex®), furosemide (Lasix®), hydrochlorothiazide, and others
- Potassium supplements or salt substitutes with potassium
- Potassium-sparing diuretics, such as spironolactone (Aldactone®), triamterene (Dyrenium®), and amiloride (Midamor®), among others
- Rifampin (Rifadin®, Rimactane®, Rofact®)
- Lithium (Eskalith®, Lithane®, Lithonate®, Lithotabs®)
- Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Motrin®, Advil®), naproxen (Naprosyn®), naproxen sodium (Aleve®, Anaprox®, Naprelan®), diclofenac (Cataflam®, Voltaren®), indomethacin (Indocin®), nabumetone (Relafen®), oxaprozin (Daypro®), celecoxib (Celebrex®), meloxicam (Mobic®), etodolac (Lodine®), ketoprofen, ketorolac (Toradol®), and others
- Fluconazole (Diflucan®).
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD