Cozaar Interactions (Cont.)

More Detail on Interactions With Cozaar

 
Diuretics
When you are taking Cozaar with a diuretic, your blood pressure may decrease too much. This is more likely to occur when Cozaar is first started. In order to decrease the chances of this Cozaar interaction, your healthcare provider may change the dosages of either medicine, start you on a lower dose of Cozaar, and/or monitor you more closely.
 
Potassium Supplements or Salt Substitutes With Potassium
If you are taking Cozaar with a potassium supplement or a salt substitute with potassium, the levels of potassium in your blood may become too high. This can cause serious problems. For your particular situation, talk to your healthcare provider about using potassium and Cozaar together.
 
Potassium-Sparing Diuretics
If you are taking both Cozaar and a potassium-sparing diuretic, your body may metabolize them differently than intended and increase the levels of potassium in your blood. Your healthcare provider may choose to monitor your progress more closely.
 
Rifampin (Rifadin, Rimactane, Rofact)
If you are taking Cozaar and rifampin together, your body may metabolize Cozaar differently than intended. This can cause a decreased level of Cozaar in your body. When using these medicines together, your healthcare provider may choose to monitor you more closely and adjust your Cozaar dose as needed.
 
Lithium (Eskalith, Lithane, Lithonate, Lithotabs)
If you are taking both Cozaar and lithium, your body may metabolize the drugs differently than intended and increase the lithium levels in the blood. Your healthcare provider may choose to monitor your blood lithium levels more frequently.
 
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
If you have kidney disease or kidney failure, taking both NSAIDs and Cozaar may add to the damage that your kidneys are already experiencing. Also, NSAIDs may decrease the blood pressure-lowering effects of Cozaar. For your particular situation, talk to your healthcare provider about using NSAIDs and Cozaar together.
(Cozaar Interactions Continued: Page 3)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;