Coreg Drug Interactions

Diphenhydramine
If you are taking Coreg and diphenhydramine together, your body may metabolize Coreg differently than intended. This can increase the level of Coreg in your body. If you are using these medicines together, your healthcare provider may choose to monitor you more closely and/or adjust your Coreg dose if needed.
 
Hydroxychloroquine
If you are taking Coreg and hydroxychloroquine together, your body may metabolize Coreg differently than intended. This can cause an increased level of Coreg in your body. If you are using these medicines together, your healthcare provider may choose to monitor you more closely and/or adjust your Coreg dose if needed.
 
Monoamine Oxidase Inhibitors (MAOIs)
Combining Coreg with an MAOI may increase the risk of low blood pressure or a slow heart rate. Check with your healthcare provider before taking such medications together.
 
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
NSAIDs may decrease the blood pressure-lowering effects of Coreg. For your particular situation, talk with your healthcare provider about using NSAIDs and Coreg together.
 
Other Beta Blockers
Coreg is a beta blocker and should not be combined with other beta blockers, as this may increase the risk of serious side effects.
 
Reserpine
Combining reserpine with a beta blocker can increase the risk of serious side effects. You may need to be monitored very closely if you take these medications together. In some cases, it is not recommended to combine Coreg with reserpine.
 
Rifampin
Rifampin can drastically decrease the level of Coreg in the blood, making it less effective. Check with your healthcare provider before taking these medications together.
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