Cardizem CD Drug Interactions (Cont.)

Cardizem CD Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Cardizem CD is combined with any of the drugs listed above.
 
Benzodiazepines
Cardizem CD can increase the level of certain benzodiazepines in your blood, possibly increasing your risk of side effects. Your healthcare provider may need to decrease your benzodiazepine dose to prevent this interaction from occurring.
 
Beta Blockers
Combining Cardizem CD with a beta blocker may increase your risk of side effects, especially low blood pressure (hypotension) and slow heart rate (bradycardia). Your healthcare provider should closely monitor your heart rate and blood pressure if you are taking a beta blocker with Cardizem CD.
 
Buspirone (BuSpar)
Cardizem CD can increase the level of buspirone in your blood, potentially increasing your risk of side effects. Your healthcare provider may need to decrease your buspirone dosage to prevent this interaction from occurring.
 
Carbamazepine (Tegretol, Tegretol XR)
Cardizem CD can increase the level of carbamazepine in your blood, possibly increasing your risk of side effects. Your healthcare provider may need to decrease your carbamazepine dosage as a result.
 
Cimetidine (Tagamet)
Cimetidine may increase the level of Cardizem CD in your blood, possibly increasing your risk of Cardizem CD side effects. Your healthcare provider may need to adjust your Cardizem CD dose or suggest an alternative to cimetidine.
 
Cyclosporine (Gengraf, Neoral, Sandimmune)
Cardizem CD may increase the level of cyclosporine in your blood, potentially increasing your risk of side effects. Your healthcare provider should monitor your cyclosporine levels and may need to adjust your dosage.
(Cardizem CD Drug Interactions Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;