Cardizem CD and Depression

In clinical studies, depression was reported as a potential side effect of Cardizem CD. Depression is common in the general population, however, so it is difficult to tell if this side effect is actually caused by Cardizem CD or other factors. If you are taking Cardizem CD and depression symptoms occur, be sure to notify your healthcare provider immediately.

 

Could Cardizem CD Lead to Depression?

Cardizem CD® (diltiazem hydrochloride) is a prescription medication known as a calcium channel blocker. It is used to treat high blood pressure (hypertension) and chest pain (known medically as angina).
 
Just like any other medicine, side effects can occur with Cardizem CD. One of these possible side effects is depression.
 

Cardizem CD and Depression: How Common Is It?

The safety and effectiveness of Cardizem CD has been studied in many people. In these clinical trials, less than 1 percent of people reported depression as a Cardizem CD side effect.
 
The challenge with Cardizem CD and depression is that given how uncommon depression is reported with the drug and how common it is within the general population, it is difficult to tell whether depression is caused by Cardizem CD, other factors, or a combination of both.
 

Cardizem CD and Depression: Recommendations

If you are taking Cardizem CD, depression may occur.
 Therefore, if you notice any possible depression symptoms while taking the drug, or if something "just does not seem right," you should talk to your healthcare provider. He or she will be able to diagnose and treat the problem. If your healthcare provider believes the medicine may be causing your symptoms, he or she may recommend another angina or blood pressure medicine.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;