If you take Brevibloc with certain other medications, interactions may occur that could increase your risk for developing a slow heart rate, dangerously slow blood pressure, cardiac arrest, or other potentially serious problems. Some of the medications that may cause drug interactions with Brevibloc include verapamil, digoxin, morphine, and succinylcholine.
Brevibloc® (esmolol hydrochloride) can potentially interact with several other medications. Some of these medicines that may lead to interactions with Brevibloc include:
- Certain "pressor" medications that are sometimes used during surgery or emergency situations, including:
- Dopamine (Intropin®)
- Epinephrine (Adrenalin®, EpiPen®)
- Norepinephrine (Levophed®)
- Digoxin (Digitek®, Lanoxin®)
- Succinylcholine (Anectine®, Quelicin®)
- Verapamil (Calan®, Calan SR®, Covera-HS®, Isoptin SR®, Verelan®, Verelan PM®)
- Warfarin (Jantoven®, Coumadin®).
Brevibloc Drug Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when Brevibloc is combined with any of the drugs listed above.
Certain Pressor Medications
If medications that constrict the blood vessels and increase the forcefulness of the heartbeat have been given, Brevibloc should not be used to control a rapid heart rate. Doing so can cause cardiac arrest.