It is ideal to start with a low dosage of Brevibloc and gradually increase the dose as needed, but this can be difficult because the medication is often used in emergency situations (in which there is not enough time to test the dosage). Dosing for this drug typically starts with one or more "loading doses," which are single, large doses given over 30 to 60 seconds each.
The dose of Brevibloc® (esmolol hydrochloride) that your healthcare provider recommends will vary depending on a number of factors, including:
- The medical condition being treated
- The urgency of the situation
- Your weight
- How you respond to the medication
- Other medications you are taking
- Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically instructs you to do so.
Ideally, a healthcare provider would have enough time to start with a low Brevibloc dosage and gradually adjust the dose until the desired results are achieved. However, since Brevibloc is often used in emergency situations, there may not be enough time for such a strategy.
Typically, dosing starts with one or more "loading doses." These are single, large doses given over 30 to 60 seconds each and are meant to rapidly control the heart rate (or blood pressure). Up to three loading doses may be given. After the loading doses, a continuous infusion (during which the medication is given at a constant rate by IV) is started.
If necessary, the Brevibloc continuous infusion may be continued for a day or two, at which time the patient should be switched to a different medication that is more appropriate for long-term use. When switching to a different medication, the Brevibloc dosage is usually reduced gradually in order to make sure that the new medication will adequately control the heart rhythm.