As a combination medication, Avalide works in two ways. The
irbesartan component is a type of angiotensin II receptor blocker (or commonly "ARB") and works by relaxing the blood vessels to improve blood flow. The
hydrochlorothiazide (
HCTZ) component is a type of diuretic and works by increasing the amount of salt and water the kidneys remove from the blood, which reduces blood volume.
Although the drug is generally well tolerated, it is not suitable for everyone. Before using Avalide, make sure your healthcare provider has up-to-date information on your medical history and a list of your current medications. In particular, make sure to let your healthcare provider know if you have problems such as kidney disease,
diabetes, or a history of an electrolyte imbalance.
(Click Avalide for more information on using this medication for high blood pressure. Topics discussed in this article include dosing guidelines, potential side effects, and safety issues to be aware of while taking this drug.)