What Is Bisoprolol and Hydrochlorothiazide Used For?

The FDA has approved bisoprolol and hydrochlorothiazide to treat high blood pressure in adults. It is a combination drug that contains a beta blocker and a diuretic, medications block a specific type of beta receptor in the body and increase the amount of salt and water that the kidneys remove from the blood. There are currently no universally accepted off-label bisoprolol and hydrochlorothiazide uses.

Bisoprolol and Hydrochlorothiazide Uses: An Overview

 Bisoprolol and hydrochlorothiazide (Ziac®) is a prescription medication licensed for the treatment of high blood pressure (hypertension). It is a combination medication that contains a diuretic (hydrochlorothiazide) and a beta blocker (bisoprolol).
 
In clinical studies, the medication has been shown to significantly lower both systolic and diastolic blood pressure. When your blood pressure is measured, the results are given as a combination of two numbers (for example, 120/80, said as "120 over 80"). The top number is the systolic blood pressure, and the bottom number is the diastolic blood pressure.
 
Medications for high blood pressure are thought to decrease the risks that occur with long-term hypertension (see Effects of High Blood Pressure). However, bisoprolol and hydrochlorothiazide does not cure high blood pressure. It is particularly useful for people who tried bisoprolol (Zebeta®) by itself but did not achieve adequate blood pressure reduction. It is also useful for people who were able to adequately lower their blood pressure with hydrochlorothiazide but experienced problems with electrolyte imbalance (adding bisoprolol can allow for the hydrochlorothiazide dosage to be reduced).
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD
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