Drug Interactions With Bisoprolol and Hydrochlorothiazide

The following sections explain in detail the potentially negative interactions that can occur when bisoprolol and hydrochlorothiazide is combined with any of the drugs listed above.

 

Drinking alcohol may increase the risk of low blood pressure with bisoprolol and hydrochlorothiazide. This may result in lightheadedness, dizziness, or fainting, particularly if you suddenly stand up. Check with your healthcare provider before combining alcohol with bisoprolol and hydrochlorothiazide.

 

Combining bisoprolol and hydrochlorothiazide with a barbiturate may increase the risk of low blood pressure. This may result in lightheadedness, dizziness, or fainting, particularly if you suddenly stand up. Check with your healthcare provider before taking these medications together.

 

Bile acid sequestrants may bind to bisoprolol and hydrochlorothiazide in the digestive tract, preventing it from being adequately absorbed. If your healthcare provider recommends that you take such medications together, it is best to separate your bisoprolol and hydrochlorothiazide dosage and the bile acid sequestrant dose by as much time as possible (by two hours at the very least).

 

Combining bisoprolol and hydrochlorothiazide with certain calcium channel blockers may cause dangerously low blood pressure and, for verapamil or diltiazem, a slow heart rate (bradycardia) and heart failure. You may need to be monitored closely if you take these medications together. In some cases, bisoprolol and hydrochlorothiazide should not be taken with a calcium channel blocker.

 

Taking bisoprolol and hydrochlorothiazide with certain arrhythmia medications may cause a dangerously slow heart rate (bradycardia). You may need to be monitored closely if you take these medications together. In some cases, bisoprolol and hydrochlorothiazide and arrhythmia medications should not be combined.