Bisoprolol and Hydrochlorothiazide

How Does Bisoprolol and Hydrochlorothiazide Work?

The bisoprolol component belongs to a group of drugs called beta-adrenergic blocking agents, more often known as beta blockers. These medications block beta receptors, which are located in a number of places within the body, including the heart and blood vessels. At lower doses in most people, bisoprolol helps to block a specific type of beta receptor called beta-1 receptors (at higher doses, it also blocks beta-2 receptors). By blocking beta-1 receptors, bisoprolol decreases both heart rate and blood pressure.
The hydrochlorothiazide component is a diuretic, which is commonly referred to as a "water pill." It works by increasing the amount of salt and water that the kidneys remove from the blood, which is then removed in the urine. As a result, hydrochlorothiazide causes a decrease in blood volume. Because of this effect, it can lower blood pressure and help with water retention.

When and How to Take It

Some general considerations to keep in mind when taking bisoprolol and hydrochlorothiazide include the following:
  • Bisoprolol and hydrochlorothiazide comes in tablet form. It is usually taken by mouth once a day.
  • You can take this medicine with a meal or on an empty stomach.
  • For the medication to work properly, it must be taken as prescribed. Bisoprolol and hydrochlorothiazide will not work if you stop taking it.
  • In general, bisoprolol and hydrochlorothiazide should not be stopped suddenly, as serious problems (including heart attacks) may result.

Dosing Information

The dose of bisoprolol and hydrochlorothiazide your healthcare provider recommends will vary, depending on a number of factors, including:
  • The severity of your high blood pressure
  • How you respond to the drug
  • Other medications you are taking
  • Other medical conditions you may have.
As always, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
(Click Bisoprolol and Hydrochlorothiazide Dosage for more information.)
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Bisoprolol and Hydrochlorothiazide Information

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