AZOR Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when
AZOR is combined with any of the drugs listed above.
ACE Inhibitors
Angiotensin II receptor blockers (ARBs), such as
olmesartan, may increase the level of potassium in the blood. Because ACE inhibitors also have this tendency, combining an ACE inhibitor with AZOR could increase the risk of high blood potassium (hyperkalemia) in some people.
Amiloride (Midamor) or Amiloride-HCTZ (Moduretic)
Combining AZOR with
amiloride products could increase your risk of high blood potassium. If your healthcare provider recommends taking these two medications together, your blood potassium levels should be closely monitored.
Angiotensin II Receptor Blockers (ARBs)
AZOR contains an ARB (olmesartan) and should generally not be combined with other ARBs, as this could increase the risk of high blood potassium or other side effects.
Eplerenone (Inspra)
Taking eplerenone with AZOR could increase your risk of developing high levels of potassium in your blood. Your healthcare provider may need to monitor your potassium levels if you take these medications together.
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
AZOR can interact with
NSAIDs in several ways. The combination could cause your
blood pressure to increase or may cause swelling (edema), especially if you have
congestive heart failure (CHF). If you are elderly, have kidney disease or kidney failure, or are taking a diuretic ("water pill") or are dehydrated, taking NSAIDs and AZOR together may cause kidney failure. Talk to your healthcare provider about this potential drug interaction before taking these medications together.
Other Blood Pressure Medications
Combining AZOR with other
high blood pressure medications may increase your risk of dangerously low blood pressure (known medically as hypotension). Diuretics ("water pills") may especially cause this problem when taken with AZOR.
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