Atacand HCT and Pregnancy

There are some situations where people should avoid taking Atacand HCT, and pregnancy is one of them. This is because during any trimester of pregnancy, Atacand HCT can lead to temporary or permanent problems, including death, in the fetus. However, Atacand HCT may still be given to a pregnant woman if her healthcare provider believes that its benefits outweigh the potential risks to the unborn child.

Is Atacand HCT Safe During Pregnancy? -- An Overview

For women who are pregnant, Atacand HCT® (candesartan cilexetil-hydrochlorothiazide) is usually not recommended. This is because during pregnancy, Atacand HCT can lead to temporary or permanent problems, including death, in the unborn child.
 

Atacand HCT and Pregnancy Category D

The U.S. Food and Drug Administration (FDA) now categorizes Atacand HCT as a pregnancy Category D medicine for all trimesters (previously, it was a Category C medicine for the first trimester and a Category D medicine for the second and third trimesters).
 
The FDA uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that show side effects to the fetus in animal studies, but no human studies in pregnant women have been done.
 
Pregnancy Category D is given to medicines that have shown clear evidence of risk to the fetus in the studies. Pregnancy Category D is a stronger warning than a pregnancy Category C classification. Despite these warnings, a pregnancy Category D medicine may still be given to a pregnant woman if her healthcare provider believes that its benefits outweigh the possible risks to the unborn child.
 

What Is the Risk of Using Atacand HCT During Pregnancy?

Some of the complications seen with fetuses or newborns exposed to Atacand HCT during pregnancy include:
 
  • Low blood pressure (hypotension)
  • Developmental problems with the nervous system
  • Developmental problems with the cardiovascular system (this includes the heart and/or blood vessels)
  • Developmental problems with the lungs
  • Kidney failure
  • Deformities of the head and face
  • Jaundice (yellowing of the skin or the whites of the eyes)
  • Loss of life.
     
Pregnancy and Pain

Atacand HCT Medicine

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