Amturnide is made by Novartis Pharmaceuticals Corporation.
As mentioned, Amturnide contains three different medications.
Amlodipine is a
calcium channel blocker. It helps slow down the rate at which
calcium moves into the blood vessel walls. This, in turn, helps to relax the vessels, which improves blood flow and lowers
blood pressure.
Aliskiren belongs to a class of drugs called renin inhibitors. Renin is an enzyme produced in the kidneys that acts throughout the body. It converts angiotensinogen to angiotensin I. A different enzyme (angiotensin-converting enzyme, or ACE) then converts angiotensin I to angiotensin II, a powerful substance that increases blood pressure by narrowing blood vessels and indirectly stimulating the kidneys to retain salt.
Hydrochlorothiazide is a diuretic, which is commonly referred to as a "water pill." It works by increasing the amount of salt and water the kidneys remove from the blood. This extra salt and water is passed out through the urine. By increasing the amount of water removed from the blood, hydrochlorothiazide decreases blood volume. Because of this effect, hydrochlorothiazide can
lower blood pressure and also help with water retention.
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