Amturnide Drug Interactions
Combining Amturnide with carbamazepine may lead to dangerously low levels of sodium in the blood. If you must take these medications together, your healthcare provider will need to monitor you closely.
Cyclosporine can significantly increase the level of aliskiren (one of the active ingredients in Amturnide) in your blood. These medications should not be taken together.
Amturnide should be used carefully in people taking digoxin. Amturnide can cause changes in potassium levels, which can be especially dangerous for people taking digoxin.
Combining Amturnide with eplerenone can increase your risk for high potassium levels in your blood (hyperkalemia). Your healthcare provider should check your potassium levels regularly. However, the hydrochlorothiazide in Amturnide can counteract this effect, since hydrochlorothiazide can cause low potassium levels, so this interaction may be somewhat unpredictable.
Itraconazole can significantly increase the level of aliskiren (one of the active ingredients in Amturnide) in your blood. These medications should not be taken together.
Taking hydrochlorothiazide (one of the active ingredients in Amturnide) with lithium may increase the level of lithium in your blood, increasing your chance of lithium side effects. In general, lithium is usually not recommended for use with diuretics, including hydrochlorothiazide. Your healthcare provider may need to monitor your lithium level more closely and adjust your dose as necessary.
Nonsteroidal Anti-inflammatory Drugs (NSAIDs)
Amturnide can interact with NSAIDs in several ways. The combination could cause your blood pressure to increase or may cause swelling (edema), especially if you have congestive heart failure (CHF). If you are elderly, have kidney disease or kidney failure, or are taking a diuretic ("water pill") or are dehydrated, taking NSAIDs and Amturnide together may cause kidney failure. Talk to your healthcare provider about this potential interaction before taking these drugs together.