Altace Drug Interactions Explained
The following section explains in detail the possible interactions that may occur when
Altace is combined with certain other substances.
ARBs
Studies suggest that combining ACE inhibitors (such as Altace) with ARBs may increase the risk of various problems (such as kidney damage, high potassium levels, or dangerously low
blood pressure) without providing significant benefit. In general, Altace should not be combined with ARB medications.
Diuretics
When taking Altace with a diuretic, your blood pressure may decrease too much. This is more likely to occur when Altace is first started. In order to decrease the chances of this interaction, your healthcare provider may change the dosages of either medicine, start you on a lower dose of Altace, and/or monitor you more closely.
Injectable Gold
Reactions have been reported in people taking Altace who received gold injections. These reactions included symptoms such as facial flushing, nausea, vomiting, and low blood pressure.
Lithium
Altace may increase the risk of
lithium toxicity and may increase the
lithium levels in the blood. Your healthcare provider may choose to monitor your blood lithium levels more frequently and may need to adjust your
lithium dosage.
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Altace can interact with
NSAIDs in several ways. The combination could cause your blood pressure to increase or may cause swelling (edema), especially if you have
congestive heart failure (CHF). If you are elderly, have kidney disease or kidney failure, or are taking a diuretic ("water pill") or are dehydrated, taking NSAIDs and Altace together may cause kidney failure. Talk to your healthcare provider about this potential drug interaction before taking these medications together.
Potassium-Containing Products
If you are taking a potassium product together with Altace, the levels of potassium in your blood may become too high. This can cause serious problems. For your particular situation, talk to your healthcare provider about using potassium and Altace together.
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