Accuretic Drug Interactions (Cont.)

 
Narcotics
When Accuretic is taken with a narcotic, your blood pressure may decrease too much. In order to decrease the chances of developing this interaction, your healthcare provider may change the dose of either medicine, start you on a lower dose of Accuretic, and/or monitor you more closely.
 
Cholestyramine (Prevalite, Questran, Questran Light, LoCholest)
Cholestyramine can bind to Accuretic in the digestive tract and decrease its absorption into the body. To avoid this drug interaction, Accuretic should be taken at least one hour before or four to six hours after cholestyramine has been given.
 
Colestipol (Colestid)
Colestipol can bind to Accuretic in the digestive tract and decrease its absorption into the body. To avoid this drug interaction, Accuretic should be taken at least one hour before or four to six hours after colestipol has been given.
 
Corticosteroids
Taking corticosteroids with Accuretic may cause an electrolyte imbalance, especially with the levels of potassium in the blood. If you are taking a corticosteroid with Accuretic, your healthcare provider may monitor you more closely and/or adjust your dose of medicine as needed.
 
Norepinephrine
Norepinephrine is a medicine that is used to treat very low blood pressure. Accuretic may affect norepinephrine's ability to raise blood pressure.
 
Corticotropin
Taking corticotropin with Accuretic may cause an electrolyte imbalance, especially with the levels of potassium in the blood. If you are taking corticotropin with Accuretic, your healthcare provider may monitor you more closely and/or adjust your dose as needed.
 
Muscle Relaxants
If you are taking both Accuretic and a muscle relaxant, your body may metabolize the drugs differently than intended and increase the muscle relaxant levels in the blood. In order to decrease the chances of developing this drug interaction, your healthcare provider may monitor you more closely and/or change the muscle relaxant dose.
 
(Accuretic Drug Interactions Continued: Page 5)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;