Accupril Drug Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when
Accupril is combined with any of the drugs listed above.
Diuretics
If you are taking Accupril with a diuretic, your
blood pressure may decrease too much. You can reduce the risk of this happening by either stopping the diuretic (under a healthcare provider's supervision) or increasing salt intake prior to starting Accupril. Talk to your healthcare provider about your specific situation for more details on these options.
Injectable Gold
Reactions have been reported in people taking Accupril who received gold injections. These reactions included symptoms such as facial flushing, nausea, vomiting, and low blood pressure.
Lithium
Accupril may increase the risk of
lithium toxicity and may increase the
lithium levels in the blood. Your healthcare provider may choose to monitor your blood lithium levels more frequently and may need to adjust your
lithium dosage.
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Accupril can interact with
NSAIDs in several ways. The combination could cause your blood pressure to increase or may cause swelling (edema), especially if you have
congestive heart failure (CHF). If you are elderly, have kidney disease or kidney failure, or are taking a diuretic ("water pill") or are dehydrated, taking NSAIDs and Accupril together may cause kidney failure. Talk to your healthcare provider about this potential drug interaction before taking these medications together.
Potassium
If you are taking a potassium product together with Accupril, the levels of potassium in your blood may become too high. This can cause serious problems. For your particular situation, talk to your healthcare provider about using potassium and Accupril together.
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