Accupril Drug Interactions (Cont.)

Accupril Interactions Explained

 

Diuretics
When taking Accupril with a diuretic, your blood pressure may decrease too much. This is more likely to occur when Accupril is first started. It order to decrease the chances of this interaction, your healthcare provider may change the dosages of either medicine, start you on a lower dose of Accupril, and/or monitor you more closely.
 
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
If you have kidney disease or kidney failure, taking both NSAIDs and Accupril may add to the damage that your kidneys are already suffering. Also, NSAIDs may decrease the blood pressure-lowering effects of Accupril. Talk with your healthcare provider about using NSAIDs and Accupril together.
 
Potassium Supplements
If you are taking a potassium supplement and Accupril, the levels of potassium in your blood may become too high. This can cause serious problems. Talk with your healthcare provider about using potassium and Accupril together.
 
Potassium-Sparing Diuretics
If you are taking both Accupril and a potassium-sparing diuretic, your body may metabolize them differently than intended or increase the levels of potassium in your blood. Your healthcare provider may choose to monitor your progress closely.
 
Lithium (Eskalith, Lithane, Lithonate, Lithotabs)
If you are taking both Accupril and lithium, your body may metabolize the drugs differently than intended and increase the lithium levels in the blood. Your healthcare provider may choose to monitor your serum lithium levels more frequently.
 
Tetracycline (Sumycin, Achromycin, Wesmycin)
Taking both tetracycline and Accupril together may decrease the amount of tetracycline in the body. If you are taking Accupril and are prescribed tetracycline, let your healthcare provider know. He or she may choose to monitor your situation more closely, consider another antibiotic, and/or adjust your dose of Accupril.
 
(Accupril Drug Interactions Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;